Internship: Defining the Role of CLN6 in Lysosomal Function and Neurodegeneration
King Abdullah University of Science and Technology (KAUST)
Saudi Arabia
Summary
Hands-on training in cellular and in vivo modeling of CLN6 disease: generate CLN6 knockout and patient-derived iPSC lines, perform ER and lysosome immunoprecipitation, and apply multi-omics to define ER–lysosome dysfunction and molecular mechanisms.