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Internship: Defining the Role of CLN6 in Lysosomal Function and Neurodegeneration

King Abdullah University of Science and Technology (KAUST)
Saudi Arabia

Summary

Hands-on training in cellular and in vivo modeling of CLN6 disease: generate CLN6 knockout and patient-derived iPSC lines, perform ER and lysosome immunoprecipitation, and apply multi-omics to define ER–lysosome dysfunction and molecular mechanisms.

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