Development and evaluation of a lung-on-a chip device for screening novel antimicrobials
Development and evaluation of a lung-on-a chip device for screening novel antimicrobials
On-going studies by our group have revealed a complex and diverse microbiota in the airways of Cystic fibrosis (CF) patients, which affects disease progression. However, mechanistic studies to determine the … Read More Read More
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Phenotypic & molecular characterization of antimicrobial resistance (AMR) markers; dissemination mechanisms of AMR in bacteria of food-animal origin; whole genome & plasmid sequencing; bioinformatics
Phenotypic & molecular characterization of antimicrobial resistance (AMR) markers; dissemination mechanisms of AMR in bacteria of food-animal origin; whole genome & plasmid sequencing; bioinformatics
Escherichia coli is a genus of bacteria, encountered as an inhabitant of the human and animal gastrointestinal tract. Surveillance is reporting an increase in resistance to all major classes of … Read More Read More
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The microbial ecology of ancient alpine soils
The microbial ecology of ancient alpine soils
Paleosols or “fossil soils” are soils that have not been disturbed by man’s activity for sometimes millions of years. They therefore harbour unique microbial populations that can be studied to … Read More Read More
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Wastewater monitoring for SARS-CoV-2 and other microbial pathogens
Wastewater monitoring for SARS-CoV-2 and other microbial pathogens
As SARS-CoV-2 is shed in high levels in faeces, wastewater testing has become a complementary, early-warning strategy for outbreaks of Covid-19, aiding governmental decision-making around future infection prevention/control policies. Wastewater … Read More Read More
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Synthesis of novel antimicrobials to kill multidrug-resistant bacteria
Synthesis of novel antimicrobials to kill multidrug-resistant bacteria
The continued emergence of antimicrobial resistance is a major global concern. The rapid development of resistance mechanisms by bacteria, as well as the lack of new structurally and mechanistically distinct … Read More Read More
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Exploiting the protein O-glycosylation pathway in opportunistic bacteria as a novel antimicrobial target
Exploiting the protein O-glycosylation pathway in opportunistic bacteria as a novel antimicrobial target
The problem. Antibiotic resistance has become a global health problem of epidemic proportions, especially for infections caused by Gram-negative bacteria. One critical need is to identify novel microbial targets that … Read More Read More
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Disarming antimicrobial responses: how Klebsiella pneumoniae controls inflammasome activation
Disarming antimicrobial responses: how Klebsiella pneumoniae controls inflammasome activation
Microbial infection triggers assembly of inflammasome complexes that promote caspase-1–dependent antimicrobial responses. This project will dissect how the antibiotic resistant pathogen Klebsiella pneumoniae evades inflammasome activation to overcome host restriction … Read More Read More
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Marie-Curie PhD scholarship in Anaerobic Microbial Consortia – DTU Chemical Engineering
Marie-Curie PhD scholarship in Anaerobic Microbial Consortia – DTU Chemical Engineering
If you are establishing your career as a scientist and you are looking for the best possible foundation for fulfilling your dreams and ambitions, it is right here in front … Read More Read More
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PhD position in microbial ecology and health during the first 1000 days of life
PhD position in microbial ecology and health during the first 1000 days of life
We are seeking a highly motivated and talented individual who is interested in contributing to our understanding of the complexity of the microbial ecosystems in relation to oral and metabolic … Read More Read More
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