Monitoring antimicrobial resistance in wastewater in Northern Ireland.
Monitoring antimicrobial resistance in wastewater in Northern Ireland.
Many biological and non-biological health associated markers can be detected in wastewater, giving an overview of prevalence of these markers in the community without the need for individual testing. Given … Read More Read More
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Chemical Tools to Tackle Antimicrobial Resistance
Chemical Tools to Tackle Antimicrobial Resistance
The School of Pharmacy and the School of Chemistry and Chemical Engineering, working under the umbrella of the Centre for Advanced Technologies for Healthcare (CATCH), are offering an exciting opportunity … Read More Read More
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Utilising data linkage to estimate antimicrobial resistance burden in paediatric populations
Utilising data linkage to estimate antimicrobial resistance burden in paediatric populations
The project will utilize data linkage techniques to link data from secondary care and primary care to evaluate antibiotic consumption and estimate antimicrobial resistance (AMR) burden in paediatric populations. Geospatial … Read More Read More
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Treatment of infections caused by multidrug-resistant Gram-negative infections through microneedle delivery of antimicrobial peptides
Treatment of infections caused by multidrug-resistant Gram-negative infections through microneedle delivery of antimicrobial peptides
Antimicrobial resistance (AMR) is a critical threat to human health and novel antibiotics and treatments are desperately needed to prevent a future pandemic. In this project, a new microneedle delivery … Read More Read More
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Covalent inhibitors of a bacterial enzyme as novel antimicrobial resistance breakers
Covalent inhibitors of a bacterial enzyme as novel antimicrobial resistance breakers
The World Health Organisation (WHO) identifies antimicrobial resistance (AMR) as one of the top 10 global threats to human health (http://www.who.int/). A recent analysis of the burden from AMR estimates … Read More Read More
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Does one size fit all for antimicrobial delivery via nanoparticles
Does one size fit all for antimicrobial delivery via nanoparticles
Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, … Read More Read More
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Improving antimicrobial delivery via nanoparticles
Improving antimicrobial delivery via nanoparticles
Antimicrobial resistant bacteria are a major issue, and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid antimicrobial drugs is by hiding … Read More Read More
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Digital design and advanced processing technologies for antimicrobial nanotherapeutics
Digital design and advanced processing technologies for antimicrobial nanotherapeutics
Fungal and bacterial infections contribute to over 7 million deaths yearly, affecting over 300 million people globally (GAFFI). Since many antimicrobial drugs are ancient, we are witnessing an unprecedented rise … Read More Read More
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Relationship between antibiotic therapy and development of antimicrobial resistance in patients with bronchiectasis and COPD
Relationship between antibiotic therapy and development of antimicrobial resistance in patients with bronchiectasis and COPD
To decrease the risk of acute infective exacerbations or flare-ups of their condition, individuals with bronchiectasis and COPD are frequently prescribed long-term oral and inhaled antibiotics. However, it is not … Read More Read More
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Development and evaluation of a lung-on-a chip device for screening novel antimicrobials
Development and evaluation of a lung-on-a chip device for screening novel antimicrobials
On-going studies by our group have revealed a complex and diverse microbiota in the airways of Cystic fibrosis (CF) patients, which affects disease progression. However, mechanistic studies to determine the … Read More Read More
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