Phenotypic & molecular characterization of antimicrobial resistance (AMR) markers; dissemination mechanisms of AMR in bacteria of food-animal origin; whole genome & plasmid sequencing; bioinformatics
Phenotypic & molecular characterization of antimicrobial resistance (AMR) markers; dissemination mechanisms of AMR in bacteria of food-animal origin; whole genome & plasmid sequencing; bioinformatics
Escherichia coli is a genus of bacteria, encountered as an inhabitant of the human and animal gastrointestinal tract. Surveillance is reporting an increase in resistance to all major classes of … Read More Read More
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The microbial ecology of ancient alpine soils
The microbial ecology of ancient alpine soils
Paleosols or “fossil soils” are soils that have not been disturbed by man’s activity for sometimes millions of years. They therefore harbour unique microbial populations that can be studied to … Read More Read More
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Wastewater monitoring for SARS-CoV-2 and other microbial pathogens
Wastewater monitoring for SARS-CoV-2 and other microbial pathogens
As SARS-CoV-2 is shed in high levels in faeces, wastewater testing has become a complementary, early-warning strategy for outbreaks of Covid-19, aiding governmental decision-making around future infection prevention/control policies. Wastewater … Read More Read More
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Synthesis of novel antimicrobials to kill multidrug-resistant bacteria
Synthesis of novel antimicrobials to kill multidrug-resistant bacteria
The continued emergence of antimicrobial resistance is a major global concern. The rapid development of resistance mechanisms by bacteria, as well as the lack of new structurally and mechanistically distinct … Read More Read More
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Exploiting the protein O-glycosylation pathway in opportunistic bacteria as a novel antimicrobial target
Exploiting the protein O-glycosylation pathway in opportunistic bacteria as a novel antimicrobial target
The problem. Antibiotic resistance has become a global health problem of epidemic proportions, especially for infections caused by Gram-negative bacteria. One critical need is to identify novel microbial targets that … Read More Read More
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Disarming antimicrobial responses: how Klebsiella pneumoniae controls inflammasome activation
Disarming antimicrobial responses: how Klebsiella pneumoniae controls inflammasome activation
Microbial infection triggers assembly of inflammasome complexes that promote caspase-1–dependent antimicrobial responses. This project will dissect how the antibiotic resistant pathogen Klebsiella pneumoniae evades inflammasome activation to overcome host restriction … Read More Read More
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Activity and toxicity of AI-Driven Antimicrobial Peptides Against WHO Priority Pathogens
Activity and toxicity of AI-Driven Antimicrobial Peptides Against WHO Priority Pathogens
Activity and toxicity of AI-Driven Antimicrobial Peptides Against WHO Priority Pathogens SUPERVISORY TEAM Supervisor Dr Kai Hilpert at City St George’s Email: khilpert@sgul.ac.uk Co-Supervisor Dr Daniel Osborn at City St … Read More Read More
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Antimicrobial Resistance (AMR) gene transfer in Methicillin Resistant Staphylococcus aureus (MRSA): mechanisms and dynamics using clinical isolates
Antimicrobial Resistance (AMR) gene transfer in Methicillin Resistant Staphylococcus aureus (MRSA): mechanisms and dynamics using clinical isolates
Antimicrobial Resistance (AMR) gene transfer in Methicillin Resistant Staphylococcus aureus (MRSA): mechanisms and dynamics using clinical isolates SUPERVISORY TEAM Supervisor Professor Jodi Lindsay at City St George’s Email: jlindsay@sgul.ac.uk Co-Supervisor … Read More Read More
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Antimicrobial resistance: what happens with age and by sex?
Antimicrobial resistance: what happens with age and by sex?
Antimicrobial resistance: what happens with age and by sex? SUPERVISORY TEAM Supervisor Dr Gwen Knight at LSHTM Email: gwen.knight@lshtm.ac.uk Co-Supervisor Dr Catrin Moore at City St George’s Email: camoore@sgul.ac.uk PROJECT … Read More Read More
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