Understanding the transcription factor network governing blood stem cell expansion
Understanding the transcription factor network governing blood stem cell expansion
About the Project Recent advances in blood stem cell expansion outside the body have afforded us an unprecedented opportunity to unravel the molecular regulators that allow a stem cell to … Read More Read More
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
About the Project Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. … Read More Read More
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Polysialyltransferases as a target in metastatic cancer
Polysialyltransferases as a target in metastatic cancer
About the Project Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Polysialic acid … Read More Read More
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The Xu lab at Georgia State University - Fully funded position available
The Xu lab at Georgia State University - Fully funded position available
About the Project The Xu lab focuses on Nanobodies. Nanobodies are antigen-binding entities derived from the heavy chain-only antibodies of camelid animals, and they retain full antigen specificity at a … Read More Read More
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Nano-scale measurement and manipulation of heat for healthcare
Nano-scale measurement and manipulation of heat for healthcare
About the Project Background The ability to measure and manipulate heat is fundamental when studying biological processes, chemical reactions and even fundamental physics. By changing temperature, biological, chemical and physical … Read More Read More
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Dynamics of the peri-nuclear actomyosin network for correct chromosome positioning in early mitosis
Dynamics of the peri-nuclear actomyosin network for correct chromosome positioning in early mitosis
About the Project To maintain genetic integrity, human cells must inherit the whole set of chromosomes without any loss or excess when the cell division takes place. To ensure this … Read More Read More
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Cancer Research Wales Fully funded 3-year PhD studentship in Cancer Cell Biology
Cancer Research Wales Fully funded 3-year PhD studentship in Cancer Cell Biology
About the Project PhD Studentship in Cancer Cell Biology Staples Lab, North West Cancer Research Institute, Bangor University We are looking for a talented PhD student to join the North … Read More Read More
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Investigate the molecular mechanism controlling FEME (Fast Endophilin Mediated Endocytosis) in directed cancer cell migration using CRISPR, biochemistry, and advanced microscopy methods.
Investigate the molecular mechanism controlling FEME (Fast Endophilin Mediated Endocytosis) in directed cancer cell migration using CRISPR, biochemistry, and advanced microscopy methods.
About the Project Cancer is a devastating disease: more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer … Read More Read More
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Investigate the switch between mesenchymal and amoeboid cancer cell migration using CRISPR-Cas9, microfluidics, and 3D live cell imaging.
Investigate the switch between mesenchymal and amoeboid cancer cell migration using CRISPR-Cas9, microfluidics, and 3D live cell imaging.
About the Project Cancer is a devastating disease: more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer … Read More Read More
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Investigate the role of NHSL1 in vesicle trafficking and receptor recycling promoting cancer cell invasion using CRISPR-Cas9, microfluidics, and advanced live cell imaging.
Investigate the role of NHSL1 in vesicle trafficking and receptor recycling promoting cancer cell invasion using CRISPR-Cas9, microfluidics, and advanced live cell imaging.
About the Project Cancer is a devastating disease: more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer … Read More Read More
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