RNA therapy development for inherited eye diseases
RNA therapy development for inherited eye diseases
About the Project Applications are welcomed for self-funded students to pursue a PhD in RNA therapeutics. The PhD project will use short activating RNAs to specifically increase target gene expression … Read More Read More
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Develop Cutting-Edge Peptide Therapies to Fight Antimicrobial Resistance in Eye Infections'
Develop Cutting-Edge Peptide Therapies to Fight Antimicrobial Resistance in Eye Infections'
About the Project The cornea, a dome-shaped, transparent tissue at the front of the eye, is crucial for vision. Corneal infections, such as bacterial keratitis (BK), are among the leading … Read More Read More
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Synthetic mRNA for re-programming and gene editing of human dental pulp stem cells
Synthetic mRNA for re-programming and gene editing of human dental pulp stem cells
About the Project 'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE' Project start date: October 1st 2025 Research Project Description: Synthetic mRNA offers a powerful and flexible reprogramming platform that can alter … Read More Read More
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Targeted dephosphorylation of hyperphosphorylated TAU in Alzheimer’s disease
Targeted dephosphorylation of hyperphosphorylated TAU in Alzheimer’s disease
About the Project Alzheimer's disease (AD) is the most common progressive neurodegenerative disorder. Despite several decades of preclinical and clinical research, few effective therapeutic approaches exist against AD. Thus, there … Read More Read More
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Unravelling the molecular mechanisms of amyotrophic lateral sclerosis / motor neuron disease
Unravelling the molecular mechanisms of amyotrophic lateral sclerosis / motor neuron disease
About the Project Amyotrophic lateral sclerosis (ALS)—the commonest type of motor neuron disease (MND)—is a rapidly progressive paralysing illness of mid-adulthood. It has a lifetime risk of ~1 in 400, … Read More Read More
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Mechanisms of Protein Phosphatase 1 regulation during oocyte meiosis
Mechanisms of Protein Phosphatase 1 regulation during oocyte meiosis
About the Project Meiosis research is of paramount importance for several aspects of human life including fertility, genetic diseases, and crop improvement. Insights into the intricate mechanisms governing the different … Read More Read More
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Phospho-regulation of kinetochore function during mitosis
Phospho-regulation of kinetochore function during mitosis
About the Project Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy, and it … Read More Read More
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How membrane proteins are regulated - revealing the dynamic S-acyl proteome in plants
How membrane proteins are regulated - revealing the dynamic S-acyl proteome in plants
About the Project S-acylation involves addition of fatty acids to sulfhydryl groups of cysteine residues within proteins, typically altering protein function by changing behaviour within cellular membranes. S-acylation is highly … Read More Read More
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Investigation of the biological behaviour and genetic regulation of rare cancers, to develop new therapies.
Investigation of the biological behaviour and genetic regulation of rare cancers, to develop new therapies.
About the Project We are an active research group investigating ocular tumours, sarcomas, and have an interest in thyroid cancer. Currently we have five PhD students who are in various … Read More Read More
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Development of new molecular therapies to treat motor neuron disease (MND)
Development of new molecular therapies to treat motor neuron disease (MND)
About the Project The battle against Motor Neuron Disease (MND) is entering an exciting phase with the development of gene therapies aimed at reducing pathogenic proteins. Our team has developed … Read More Read More
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