NMR characterization of the Tau/14-3-3 interface and modulation of this PPI by small molecules in the context of Alzheimer’s disease
NMR characterization of the Tau/14-3-3 interface and modulation of this PPI by small molecules in the context of Alzheimer’s disease
Job Information Organisation/Company CNRS UMI Meknès Research Field Chemistry » Biochemistry Chemistry » Biochemistry Researcher Profile First Stage Researcher (R1) Country France Application Deadline 1 Jan 2999 - 23:59 (UTC) … Read More Read More
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Targeted dephosphorylation of hyperphosphorylated TAU in Alzheimer’s disease
Targeted dephosphorylation of hyperphosphorylated TAU in Alzheimer’s disease
About the Project Alzheimer's disease (AD) is the most common progressive neurodegenerative disorder. Despite several decades of preclinical and clinical research, few effective therapeutic approaches exist against AD. Thus, there … Read More Read More
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Generation of novel, venom-derived ion channel modulators to target pain and neurodegenerative pathways
Generation of novel, venom-derived ion channel modulators to target pain and neurodegenerative pathways
About the Project Applications are invited for this self-funded PhD project within the Institute of Medical Sciences at the University of Aberdeen. Neuropathic pain (NP) is a debilitating chronic pain … Read More Read More
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Modelling hair lubrication in the presence of additives
Modelling hair lubrication in the presence of additives
About the Project This project is sponsored by the Institute of Chemical Biology EPSRC Centre for Doctoral Training and Procter & Gamble This is a 3-year PhD project, available for … Read More Read More
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Investigating bacteria-bacteriophage diversity to develop phage libraries for treatment of bacterial infections
Investigating bacteria-bacteriophage diversity to develop phage libraries for treatment of bacterial infections
About the Project Project Overview The World Health Organisation (WHO) predicts antimicrobial resistant (AMR) infections will be the leading cause of death globally by 2050. Bacteriophages, or “phages”, are viruses … Read More Read More
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Unravelling the molecular mechanisms of amyotrophic lateral sclerosis / motor neuron disease
Unravelling the molecular mechanisms of amyotrophic lateral sclerosis / motor neuron disease
About the Project Amyotrophic lateral sclerosis (ALS)—the commonest type of motor neuron disease (MND)—is a rapidly progressive paralysing illness of mid-adulthood. It has a lifetime risk of ~1 in 400, … Read More Read More
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Mechanisms of Protein Phosphatase 1 regulation during oocyte meiosis
Mechanisms of Protein Phosphatase 1 regulation during oocyte meiosis
About the Project Meiosis research is of paramount importance for several aspects of human life including fertility, genetic diseases, and crop improvement. Insights into the intricate mechanisms governing the different … Read More Read More
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Phospho-regulation of kinetochore function during mitosis
Phospho-regulation of kinetochore function during mitosis
About the Project Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy, and it … Read More Read More
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How membrane proteins are regulated - revealing the dynamic S-acyl proteome in plants
How membrane proteins are regulated - revealing the dynamic S-acyl proteome in plants
About the Project S-acylation involves addition of fatty acids to sulfhydryl groups of cysteine residues within proteins, typically altering protein function by changing behaviour within cellular membranes. S-acylation is highly … Read More Read More
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Developing an advanced microscopy platform to study protein aggregates in neurons
Developing an advanced microscopy platform to study protein aggregates in neurons
About the Project Department of Brain Sciences at Imperial PhD studentship in advanced fluorescence microscopy to study Parkinson’s disease and dementia with Lewy bodies, Imperial College London Applications are invited … Read More Read More
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