Determining the molecular drivers of conformational interconversion for kinase inhibitor binding
Determining the molecular drivers of conformational interconversion for kinase inhibitor binding
About the Project Protein kinases are central to many cellular processes (eg cell division and the response to external signals) and are current drug targets in cancer, cardiac and inflammatory … Read More Read More
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Modular DNA nanopores for synthetic biology
Modular DNA nanopores for synthetic biology
About the Project The aim of this project is to develop artificial cells that can programmably communicate. In biology, cells are miniature factories where different compartments handle specific tasks. Directed … Read More Read More
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Mathematical Signal Processing and Machine Learning approaches to understand and define the abnormal heart tissue responsible for fatal heart rhythms
Mathematical Signal Processing and Machine Learning approaches to understand and define the abnormal heart tissue responsible for fatal heart rhythms
About the Project Find out more and apply now Sudden cardiac arrest (SCA) accounts for approximately 15-20% of reported deaths in the UK. Those most effected by SCA are people … Read More Read More
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How do RNA-binding proteins control splice site selection? A multi-disciplinary approach
How do RNA-binding proteins control splice site selection? A multi-disciplinary approach
About the Project Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression … Read More Read More
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Novel method development and applications in Electron Paramagnetic Resonance
Novel method development and applications in Electron Paramagnetic Resonance
About the Project A 4-year PhD studentship in novel method development and applications in Electron Paramagnetic Resonance (EPR) is available in the group of Dr Alice Bowen. It is supported … Read More Read More
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Peptidomimetic Inhibitors of Protein-Protein Interactions – A Sustainable Approach
Peptidomimetic Inhibitors of Protein-Protein Interactions – A Sustainable Approach
About the Project Transient protein-protein interactions (PPIs) control all cellular processes (e.g. mitosis) (1) relevant to health and disease. Thus, a major problem in life-sciences research is to understand and … Read More Read More
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Deep Learning and Innovative Optical Microscopy to Uncover Cancer Electrostatics
Deep Learning and Innovative Optical Microscopy to Uncover Cancer Electrostatics
About the Project Location: University of Nottingham, Faculty of Engineering | Funding: Fully funded for UK students; partial competitive funding for international students | Start Date: April or October 2025 … Read More Read More
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Ion channel signalling in cancer cells
Ion channel signalling in cancer cells
About the Project Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to … Read More Read More
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Computer-aided Precision Surgery: Medical Image Guided Surgical Planning and Targeted Drug Delivery About this Project
Computer-aided Precision Surgery: Medical Image Guided Surgical Planning and Targeted Drug Delivery About this Project
About the Project About this Project: Image-guided surgery utilises pre-operative and/or intraoperative medical imaging data to help visualise and navigate surgical instrument and tools in reaching the targeted sites of … Read More Read More
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Nano-scale measurement and manipulation of heat for healthcare
Nano-scale measurement and manipulation of heat for healthcare
About the Project Background The ability to measure and manipulate heat is fundamental when studying biological processes, chemical reactions and even fundamental physics. By changing temperature, biological, chemical and physical … Read More Read More
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